T1 weighted imaging

In T1 weighted imaging (T1WI) fluid is dark. There are a few specific things that are bright on T1WI.

mod1_T1WI

Bright on T1WI

Things that are bright on T1WI:

  • fat
  • blood (depending on age)
  • protein
  • melanin
  • gadolinium
  • some calcium

Dark on T1WI

  • fluid
  • fibrosis / sclerosis

But, hold on ...

If fluid is dark on both T1WI and on FLAIR, how do I tell which sequence I’m looking at? The way that I have found to be the most useful is the relative signal of CSF, white matter and grey matter.

When working in-to-out (CSF > white matter > grey matter) on both T1WI and T2WI the signals alternate (dark > bright > dark and bright > dark > bright respectively). FLAIR, however, does not (dark > dark >bright).

mod1_T1_T2_FLAIR_comparison